Discuss the following: Maternal predisposition teratogenic exposure
Discuss the following: Maternal predisposition teratogenic exposure (what factors may cause the syndrome) Explain the clinical and sonographic findings associated with the syndrome
Discuss the following: Maternal predisposition teratogenic exposure
Please explain this fatal syndrome: Amniotic band syndrome
Discuss the following:
1. Maternal predisposition / teratogenic exposure (what factors may cause the syndrome)
2. Explain the clinical and sonographic findings associated with the syndrome
The paper length should include one or two small sonographic images with explanation of the image.
The paper should be properly cited as well as the images. ( APA)
More Details:
Mechanisms of Teratogens in the Causation of Malformations
Teratogens affect morphogenesis, development and differentiation through cell death, failed cell interactions or alterations in the movement of cells.
As these affect the basic processes of cells, not only may a teratogen have a general effect on several tissues, but different teratogens may produce common effects. Some teratogens do, however, produce a characteristic pattern of anomaly.
For example carbimazole for the treatment of thyrotoxicosis causes choanal atresia, cutis aplasia with distinctive facial features.
All women should be aske d about drug exposure both therapeutic and recreational, as well as over-the-counter medications whose availability vary considerably between countries.
A teratogen is an environmental agent that can cause abnormalities in an exposed fetus.
The effects depend on the nature of the teratogen, the timing at which the exposure occurs and, most likely, the genetic susceptibility of the mother and/or the fetus.
Teratogenic agents can be environmental chemicals, maternal metabolic factors, drugs, or infections.
A number of environmental chemicals have been linked with birth defects in exposed fetuses including lead, methyl mercury, and polychlorinated biphenyls.
Maternal metabolic factors associated with a significant risk of birth defects are maternal diabetes and maternal phenylketonuria.
Lastly, teratogens are chemical, physical, or biologic agents that are able to induce developmental abnormalities.